Kaplan-Meier Plotter

Pancreatic cancer Breast cancer Ovarian cancer Lung cancer Gastric cancer Colon cancer AML Myeloma Liver cancer Pan-cancer Breast cancer Breast cancer Liver cancer Pan-cancer Breast cancer Custom Pan-cancer DNA Immunotherapy

Select mutation:	All mutation Disruptive mutation
	Single gene
	Cancer hallmarks			Sustained angiogenesis Tumor-promoting inflammation Genome instability Sustaining proliferative signaling Evading immune destruction Replicative immortality Resisting cell death Evading growth suppressors Reprogramming energy metabolism Tissue invasion and metastasis
	Custom geneset			Add
	GO biological process
	No. mutations
Survival:	Overall survival Disease free survival

Using the selected parameters, the analysis will run on

4586

patients.

	Event	Censored
Mutant	-	-
Wildtype	-	-

Include following samples:

Stage (n=4056)	Any	S1	S2	S3	S4
T (n=2915)	Any	T1	T2	T3	T4
N (n=3428)	Any	N0	N1	N2	N3
M (n=4077)	Any	M0	M1

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Filter for:

ER status	Any Positive (n=3661) Negative (n=873)
HER2 status	Any Positive (n=599) Negative (n=3812)

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n = number of patients with available clinical data

Please kindly cite following paper to support further development: Posta M, Győrffy B. Pathway-level mutational signatures predict breast cancer outcomes and reveal therapeutic targets, British Journal of Pharmacology, 2025;1-14., https://doi.org/10.1111/bph.70215